The National Gene Vector Laboratories (NGVL) are composed of an interactive group of academic production and toxicology laboratories whose primary goal is to provide eligible investigators with clinical grade vectors for Phase I/II gene therapy clinical trials and to provide support for relevant toxicology studies leading up to clinical gene transfer protocols.

Requests are accepted by the NGVL for retrovirus, adenovirus, adeno-associated virus, DNA plasmid, herpesvirus, lentivirus and other novel vectors.

NIH SUPPORTING INSTITUTES

Production of these viral vectors and/or toxicology studies is supported by:

• National Center for Research Resources (NCRR)
• National Cancer Institute (NCI)
• National Institute of Diabetes and Digestive Kidney Diseases (NIDDK)
• National Institute of Allergy & Infectious Diseases (NIAID)
• National Institute of Child Health & Human Development (NICHD)
• National Institute of Arthritis & Musculoskeletal & Skin Diseases (NIAMS)
• National Institute of Neurological Disorders & Stroke (NINDS)
• National Institute of Dental & Craniofacial Research (NIDCR)
• National, Heart, Lung and Blood Institute (NHLBI)
• National Institute of Environmental Health Sciences (NIEHS)
• Office of Rare Diseases (ORD)